Study pans long-term antibiotic therapy for “chronic Lyme disease”

Posted 11 April 2016

Another study has confirmed the futility of long-term antibiotic therapy for people with symptoms attributed to “chronic Lyme disease.” This study involved 252 patients who received 2 weeks of standard antibiotic treatment followed by 12 weeks in which they received either doxycycline, another antibiotic, or a placebo. The three groups demonstrated no significant differences in outcome. [1]

An accompanying editorial concluded: “Patients with subjective, vexing symptoms attributed to Lyme disease should not anticipate that even longer courses of antibiotics will produce relief, a finding that is in concert with results from previous trials.” [2]


  1. Berende A and others. Randomized trial of longer-term therapy for symptoms attributed to Lyme disease. New England Journal of Medicine 2016;374:1277-1288.
  2. Melia TM, Auwaerter PG. Time for a different approach to Lyme disease and long-term symptoms. New England Journal of Medicine 2016;374:1277-1288.
[Source: Consumer Health Digest #16-13, April 10,  … Read the rest