Tag Archives | Fish oil

Fish oil supplementation not supported in new meta-analysis

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Posted 27 June 2018

A meta-analysis of 10 randomized controlled trials involving 77,917 individuals found no evidence that a mean of 4.4 years of supplementation with marine-derived omega-3 fatty acids was effective in preventing fatal or nonfatal coronary heart disease, strokes, or the need for procedures to restore circulation. The supplementation was also ineffective in preventing these cardiovascular outcomes in subgroups of individuals at elevated risk.

Reference: Aung T. Associations of omega-3 fatty acid supplement use with cardiovascular disease risks. JAMA Cardiology 3:225-234, 2018

The findings do not support the conclusion of a 2017 science advisory from the American Heart Association which suggested that fish oil supplementation is reasonable treatment for people with coronary heart disease but was based on only one trial of patients with heart failure. Both the 2017 science advisory and the new meta-analysis agreed that there is no evidence of benefit from fish oil supplementation Read the rest

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Any benefit for fish oil, omega-3 supplements or curcumin?

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Posted 09 March 2018

“Fish oil or omega-3 supplements won’t help people with heart disease,” writes nutritionist Alice Callahan in Lifehacker. Her source is a recent JAMA Cardiology meta-study that looked at 10 trials with a total of 77, 917 participants and found that “supplementation with marine-derived omega-3 fatty acids for a mean of 4.4 years had no significant association with reductions in fatal or nonfatal coronary heart disease or any major vascular events.”

For years and years, people have sworn by the yellowing agent in turmeric as an exceptionally potent natural remedy for almost everything. But as Derek Lowe noted last year, “no curcumin trial has ever reported any convincing positive results.” 

Read these extracts in the context of the full article published in Reason

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Nutraceuticals and skin appearance: Is there any evidence to support the claims?

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Posted 15 February 2018

“The rise of the nutraceutical market, specifically oral nutrition supplements claiming to improve skin appearance, is striking. This paper aims to examine the published scientific evidence for beneficial effects of nutraceuticals on skin appearance. An overview of skin physiology and intrinsic and extrinsic ageing is provided which underlies the potential physiological processes nutraceuticals purport to counter”.

“Current evidence for those without existing authorised claims (e.g. green tea extract, pomegranate extract, carotenoids, evening primrose oil, borage oil, fish oil, collagen and co-enzyme Q10) is reviewed, focussing primarily on evidence from randomised controlled trials where available, in relation to skin parameters including wrinkles and hydration”. 

“To date, the evidence for many ingredients in relation to skin appearance is limited, not sufficiently robust and/or inconsistent. Although there are a small number of human studies suggesting a potential benefit and some plausible biological mechanisms, much of the evidence Read the rest

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Supplements and Safety

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Posted 21 January 2016

The New York Times has published an article written by Anahad O’Connor, titled, ‘Supplements and Safety’ Explores What’s in Your Supplements, asking the question: do you know what is in your supplements, and in particular, what is in your fish oil?

A new documentary, “Supplements and Safety,” pulls back the curtain on some of America’s most popular supplements, and it suggests that many people who buy them may not be getting what they are paying for. The program, airing on the PBS investigative series “Frontline” on Tuesday night, is a collaboration between “Frontline,” The New York Times and The Canadian Broadcasting Corporation.

The program examines the widespread use of potent vitamins, herbs, fish oil and fat-burning supplements. Millions of Americans use these products safely every year. But researchers have found that in many cases they can cause unexpected side effects. And because dietary

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Fish Oil Claims Not Supported by Research

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Posted 31 March 2015

By Anahad O’Connor
March 30, 2015 5:06 pm

“Fish oil is now the third most widely used dietary supplement in the United States, after vitamins and minerals, according to a recent report from the National Institutes of Health. At least 10 percent of Americans take fish oil regularly, most believing that the omega-3 fatty acids in the supplements will protect their cardiovascular health. 

But there is one big problem: The vast majority of clinical trials involving fish oil have found no evidence that it lowers the risk of heart attack and stroke.”

Continue reading this article published in the New York Times.

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Fish oil and other supplements

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In his column in The Guardian, Dr Ben Goldacre writes:

“This week the food and nutrition pills industries are complaining. They like to make health claims about their products, which often turn out to be unsupported by the evidence. Regulating that mess would be tedious, the kind of project enjoyed by the EU. Enter Nutrition and Health Claims Regulation in 2006.Since then member states have submitted thousands of health claims for manufacturers about cranberries, fish oil and every magical ingredient you can think of. This week it turned out that 900 have been examined so far, of which 80% have been rejected.”

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