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Can Supplements Really Help With Depression or Anxiety?

Posted 17 June 2022

SCAM OR NOT

Here’s what the evidence says about what works (and what doesn’t).

St. John’s wort “promotes a positive mood.” Valerian root reduces “levels of anxiety and stress.” Lavender oil is “calming for body and mind.”

If you are among the tens of millions of people in the United States who suffer from depression or anxiety, it is easy to be captivated by the promise of mood-boosting supplements. Take these pills daily, their marketing suggests, and soon you’ll be happily bouncing through verdant, sun-soaked fields, no prescription required.

But, while experts say that some mood-lifting supplements are better studied than others, the wider evidence on their effectiveness is shaky at best. “I’m not saying that there’s evidence that these things aren’t useful,” said Dr. Gerard Sanacora, a professor of psychiatry at the Yale School of Medicine

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Does high-dose Omega-3 Fatty Acids protect against adverse cardiovascular events?

Posted 16 November 2020

Conclusion:
Among statin-treated patients at high cardiovascular risk, the addition of omega-3 CA, compared with corn oil, to usual background therapies resulted in no significant difference in a composite outcome of major adverse cardiovascular events. These findings do not support use of this omega-3 fatty acid formulation to reduce major adverse cardiovascular events in high-risk patients.

Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk – The STRENGTH Randomized Clinical Trial

JAMA. Published online November 15, 2020. doi:10.1001/jama.2020.22258

Key Points

Question  In statin-treated patients with high cardiovascular risk, high triglycerides, and low HDL cholesterol levels, does adding a carboxylic acid formulation of omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) to background therapy improve cardiovascular outcomes?

Findings  In this randomized clinical trial of 13 078 patients that was stopped early, daily supplementation with omega-3 Read the rest