Why microbiome tests are currently of limited value for your clinical practice

Posted 29 July 2022

This article concludes:

Microbiome testing is still in its infancy. Here is a summary of some clinical takeaways that you can explain to your patients the next time they ask about the utility of microbiome tests:

  • Scientists have not yet defined a healthy or normal gut microbiome that can reliably predict whether a person will develop a particular disease.
  • Relying on stool samples for studying the gut microbiome is inaccurate as the microbiome in stool does not faithfully reflect the microbiome at the intestinal mucosa. The stool microbiome is stable over time and different from the luminal microbiome, which varies depending on each part of the gastrointestinal tract.
  • Some commercial microbiome test reports describe the patient’s gut microbiome profile in terms of “good” and “bad” bacteria. The behavior of a particular gut microbe depends on the environment in which it lives and interactions with other commensal
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DNA Diet – Dnalysis still ‘duping’ clients?

Posted 19 July 2022

Dnanalysis continues to claim efficacy for the genetic testing and diet/weight-loss efficacy.

On the website, they claim “DNA Diet® is a genetic test designed to guide the personalisation of diet and lifestyle recommendations in order to manage weight. It provides insight into which diet type (low carbohydrate, low fat, or Mediterranean diet) would be most suitable for you according to your unique genetic makeup.”

Yet years after starting with these claims, the evidence to back up claims that a DNA test can assist with weight-loss or weigh management remains very thin.

Read the original article at The Conversation

Here is the most recent article rebutting these claims:

But, as people got older, we also noticed differences in their weight that couldn’t be explained by genetics or social background. This meant that neither of those factors is a good predictor of any particular person’s body weight.

Our Read the rest

Study looks at tainted dietary supplements

Posted 06 July 2022

The U.S. Food and Drug Administration’s Tainted Supplements Database, created in 2007, lists products adulterated with active pharmaceutical ingredients (APIs). Between 2007 and 2021, 1,068 unique dietary-supplement products were added to the database. A recent study has found that the products likely to include APIs were for sexual enhancement and weight loss.

The author noted:

  • Since 2016, the percentage of products containing more than one API has increased.
  • Since 2016, the percentage of adulterated products for sexual enhancement was higher, the percentage of weight-loss products was lower, and no muscle-building products were reported.
  • Some products with APIs were removed from the market by the FDA because the risks were too great, some were never reviewed by the FDA, and some combined multiple APIs in ways that make it impossible to determine how benefits compare to harms.

Continued Risk of Dietary Supplements Adulterated With Approved and … Read the rest

Immune Boosters – Scam?

Posted 05 July 2022

A number of products claim to be immune boosters.

These reputable articles argue that these claims are invalid and not physiologically possible – unless you are undernourished or malnourished.

BBC: Covid-19: Can ‘boosting’ your immune system protect you?

“Unfortunately, the idea that pills, trendy superfoods or wellness habits can provide a shortcut to a healthy immune system is a myth. In fact, the concept of “boosting” your immune system doesn’t hold any scientific meaning whatsoever.”


Cedars Sinai Hospital: Can You Really Boost Your Immune System?

“Dr. Cassel says most of the things people take to boost their immune system, such as vitamins or supplements, don’t have any effect on your immune response.”


Science Based Medicine: Boost Your Immune System?

“The immune system is not a muscle, not a rocket, not a pump, not a balloon, nor anything else that can be inflated, expanded, or … Read the rest